Core Facilities
Saarland University
NGS Sequencing Facility (NSF)
The NGS Sequencing Facility (NSF) of Saarland University, that orginated from the 2018 founded sequencing lab of the Chair for Clinical Bioinformatics, offers service and guidance in the area of high throughput sequencing to its users.
Element Analysis & Mass Spectrometry
The Core Facility Elemental Analysis & Mass Spectrometry on the Saarbrücken Campus at Saarland University has modern methods for high-resolution structural elucidation of natural and synthetically produced organic and inorganic molecules as well as methods for mass determination and determination of functional groups in macromolecular systems... Read more
EpiGenomics Sequencing Facility (ESF)
TheEpiGenomics Sequencing Facility (ESF)at Saarland University offers a wide range of state-of-the-art technologies in the field ofnext-generation sequencing (NGS)andthird-generation sequencing. We offer a wide range of methods, including genome analysis, DNA methylation, histone modification, chromatin accessibility and RNA expression.
FACS & Particle Analysis
The Core Facility combines expertise in the field of preparative and analytical sort of cells and particles as well as follow up of molecular and functional analysis. Various FACS and particle sorting and analysis systems are available for the analysis and sorting of single cell suspensions (e.g. single cell cloning, complex immunological... Read more
Correlative Microscopy and Tomography (CoMiTo)
TheCorrelative Microscopy and TomographyEquipment Centre at Saarland University provides advanced methods of quantitative microstructure analysis in 2D and 3D, as well as methods of micro- and nanomechanical characterisation. It is supported by three chairs, which contribute their respective expertise and equipment to the centre.
Mass Spectrometry
The Mass Spectrometry Core Facility provides bioanalytical methods, particularly OMICS analyses (small molecules, peptides, proteins), and continuously develops and establishes new techniques. The Facility is equipped with an array of mass spectrometers, including Orbitrap Eclipse, Q Exactive Plus, and timsTOF with (nano)-LC coupling. As a... Read more
Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)
NGS Sequencing Facility (NSF)
The NGS Sequencing Facility (NSF) of Saarland University, that orginated from the 2018 founded sequencing lab of the Chair for Clinical Bioinformatics, offers service and guidance in the area of high throughput sequencing to its users.
Robotics & Liquid Handling Facility
The Robotics & Liquid Handling Facility offers a comprehensive, highly automated infrastructure for precise and reproducible liquid handling at HIPS. At the heart of the platform is an ACCESS workstation from Beckman Coulter, centred around the ECHO 650T. This instrument enables completely contactless liquid transfer using focused acoustic... Read more
Zebrafish Facility
Zebrafish (Danio rerio) are among the most important non-mammalian vertebrate model organisms. Their larvae are especially useful for early drug discovery because they develop rapidly, are robust, and remain naturally transparent—enabling real-time visualization of biological processes. Importantly, zebrafish larvae support the 3R principles... Read more
Joint Facilities
High Resolution Microscopy
The Core Facility 'High Resolution Microscopy' is part of the interfaculty Center for Biophysics (ZBP) on the Saarbrücken campus. It is open to all scientists at the university and offers a broad spectrum of optical microscopy for both fixed samples and live cell microscopy. Instruments of different resolution classes are available,... Read more
NMR Spectroscopy
As a core facility, the NMR service centre looks after all NMR spectrometers in the chemistry and pharmacy departments at Saarland University. It organises the entire measurement volume both in automated service operation and through in-house measurements. In addition, we offer complete data management from the online provision of all measurement... Read more
Advanced Light Microscopy (ALM-CF)
To understand the secret of Ca2+ signalling in cardiomyocytes, we investigate the elementary Ca2+ release units (CRUs) in electrically stimulated Ca2+ transients of cardiomyocytes. We first isolate the elemental Ca2+ releases from these CRUs in cardiac Ca2+ transients using advanced methods and then quantify the effects of physiological or... Read more